Question 1 · Clinical nursing practice
A patient taking lithium has coarse tremor, vomiting, diarrhoea and new confusion. What should the nurse suspect?
- A.Lithium toxicity: hold the next dose and get urgent review
- B.Expected side effects of lithium, which usually settle within a few weeks
- C.Serotonin syndrome: stop the antidepressants and recheck in 24 hours
- D.Bipolar relapse: increase the lithium dose and inform the team
Show answer and explanation
✓ Answer: A. Lithium toxicity: hold the next dose and get urgent review
Coarse tremor, GI upset, confusion, ataxia and slurred speech suggest lithium toxicity. Hold the next dose and arrange urgent review and serum levels. The usual target range is 0.4–1.0 mmol/L, taken 12 hours after the dose. Dehydration, NSAIDs, ACE inhibitors and diuretics raise lithium levels.